Engineered to target the cancer, not the patient

BiVictriX is building a novel pipeline of first-in-class therapeutics that have superior cancer selectivity. By significantly reducing harmful side-effects, we aim to vastly improve the safe dose of anti-cancer drugs patients can withstand, thus improving the overall effectiveness of treatment at eradicating the cancer.

Our approach relies on utilising our proprietary library of cancer-specific “twin antigen fingerprints”, which are uniquely expressed on the cancer; enabling them to be selectively targeted, while leaving healthy cells alone.

By applying this science, we created our Bi-Cygni® therapeutics.

We are unique in that we identify cancer-specific “fingerprints”, novel combinations of antigens which are co-expressed on the cancer cells but which are largely absent on healthy cells.

Coupled with this knowledge, we use our specialist know-how to design next-generation obligate bispecific therapeutics, capable of selectively targeting the cancer-specific “fingerprints” identified. Thereby fully exploiting the benefits of this promising approach.

The next phase in targeted cancer therapy

Significant benefits offered by Bi-Cygni® therapeutics

Significantly reduced toxicity enables higher dosing and greater efficacy
Superior potency achieved through targeting dual antigens
Reduced toxicity expands options for combinatorial therapies
Expands the universe of potential drug targets
Adaptable across solid/liquid cancers, not reliant on tumour microenvironment
Effective across both high and low expressing tumours

BIVICTRIX WHOLLY OWNED PIPELINE

Discovery
Preclinical
IND Enabling

SOLID TUMORS

 

BVX002
B7H4xTarget B
Bispecific ADC
Indications: Ovarian Cancer & Other Solid Tumors
Milestones: 2H 2026 – IND submission

BVX004
Undisclosed
Bispecific ADC
Indications: Multiple Solid Tumor

Bispecific
ADC Target Library
Indications: Multiple Tumor Indications
Target pair library identified across multiple solid tumor indication

HEMATOLOGICAL MALIGNANCIES

 

BVX001¹
CD7 x CD33
Bispecific ADC
Indications: Acute Myeloid Leukemia & Myelodysplastic Syndrome
Partnership Candidate

  1. Orphan drug designation granted in April 2024.